CYANOKIT

LOE Approaching

hydroxocobalamin

NDAINJECTIONINJECTABLEPriority Review
Approved
Dec 2006
Lifecycle
LOE Approaching
Competitive Pressure
30/100

Mechanism of Action

poison. In the absence of rapid and adequate treatment, exposure to a high dose of cyanide can result in death within minutes due to the inhibition of cytochrome oxidase resulting in arrest of cellular respiration. Specifically, cyanide binds rapidly with cytochrome a3, a component of the…

Pharmacologic Class:

Antidote