NDAORALTABLET
Approved
Apr 2022
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
3
Data completeness
5/8 — Partial
Drug data last refreshed 7h ago · AI intelligence enriched 3w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
CUVRIOR (trientine tetrahydrochloride) is an oral small-molecule chelating agent approved in April 2022 for Wilson disease, a rare genetic disorder of copper metabolism. It binds and facilitates urinary excretion of excess copper, preventing neurological and hepatic damage. The drug represents a key treatment option for patients with copper overload who require long-term maintenance therapy.
$0.378MPart D
Peak12.7 years to LOEDrug is in peak lifecycle phase with minimal direct competition and no generic threat until 2039, supporting stable team size and predictable commercial strategy.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (3)
Trientine Tetrahydrochloride Administered Once a Day for the First Line Treatment of Wilson's Disease Patients.
Started Jul 2026
38 enrolled
Wilson's Disease
Patient Preference Study: Standard of Care Versus Once-daily Trientine Tetrahydrochloride
Started Jul 2025
10 enrolled
Wilson's Disease
Trientine Tetrahydrochloride (TETA 4HCL) for the Treatment of Wilson's Disease
Started Sep 2018
77 enrolled
Wilson Disease
Career Relevance
CUVRIOR roles are concentrated in IT and Commercial functions with emerging emphasis on AI/analytics capabilities, suggesting the team is building data intelligence infrastructure for rare disease market penetration and patient identification. Career opportunities emphasize digital transformation and commercial analytics rather than traditional medical affairs or sales roles.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.