CUVRIOR

Peak

trientine tetrahydrochloride

NDAORALTABLET
Approved
Apr 2022
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
3

Mechanism of Action

Trientine, a copper chelator, eliminates absorbed copper from the body by forming a stable complex that is then eliminated through urinary excretion. Trientine also chelates copper in the intestinal tract, reducing copper absorption.

Clinical Trials (3)

NCT07465718Phase 3Not Yet Recruiting

Trientine Tetrahydrochloride Administered Once a Day for the First Line Treatment of Wilson's Disease Patients.

Started May 2026
38 enrolled
Wilson's Disease
NCT07010575Phase 2Completed

Patient Preference Study: Standard of Care Versus Once-daily Trientine Tetrahydrochloride

Started Jul 2025
10 enrolled
Wilson's Disease
NCT03539952Phase 3Completed

Trientine Tetrahydrochloride (TETA 4HCL) for the Treatment of Wilson's Disease

Started Sep 2018
77 enrolled
Wilson Disease

Loss of Exclusivity

LOE Date
May 3, 2039
160 months away
Patent Expiry
May 3, 2039
Exclusivity Expiry
Apr 28, 2029

Patent Records (4)

Patent #ExpiryTypeUse Code
10988436
May 3, 2039
Substance
11072577
May 3, 2039
U-3370
12358861
May 3, 2039
SubstanceProduct
U-4262
12358862
May 3, 2039
SubstanceProduct
U-4262