NDAVAGINALGEL
Approved
Jul 1997
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20
Data completeness
5/8 — Partial
CRINONE (progesterone) by AbbVie is clinical pharmacology progesterone is a naturally occurring steroid that is secreted by the ovary, placenta, and adrenal gland. Approved for infertility, contraception, osteoporosis and 5 more indications. First approved in 1997.
Drug data last refreshed 20h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
CRINONE is a vaginal gel formulation of progesterone, a naturally occurring steroid essential for endometrial transformation and embryo implantation. It is used to support infertility treatment, prevent miscarriage, manage menopausal symptoms, and treat various gynecological conditions. Progesterone works by transforming the endometrium into a secretory state and maintaining pregnancy once implantation occurs.
$71KPart D
LOE ApproachingDeclining
Minimal Part D utilization and approaching loss of exclusivity indicate a mature, low-revenue product with declining team investment.
Mechanism of Action
CLINICAL PHARMACOLOGY Progesterone is a naturally occurring steroid that is secreted by the ovary, placenta, and adrenal gland. In the presence of adequate estrogen, progesterone transforms a proliferative endometrium into a secretory endometrium. Progesterone is essential for the development of…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.