NDAINTRAVENOUSSOLUTION
Approved
Feb 2008
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
1
Mechanism of Action
CLINICAL PHARMACOLOGY Cosyntropin, like ACTH, binds specific receptors in the plasma membrane of adrenal cortical cells in the zona fasciculata. The hormone-receptor complex activates adenylate cyclase, which stimulates the production of cyclic AMP. This leads to the conversion of cholesterol to…
Clinical Trials (1)
Cosyntropin Versus Epidural Blood Patch (EBP) for Treatment of Treatment of Post Dural Puncture Headache
Started Aug 2010
29 enrolled
Postdural Puncture Headache