COSOPT

LOE Approaching

dorzolamide hydrochloride and timolol maleate

NDAOPHTHALMICSOLUTION/DROPS
Approved
Apr 1998
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
11

Mechanism of Action

components: dorzolamide hydrochloride and timolol maleate. Each of these two components decreases elevated intraocular pressure, whether or not associated with glaucoma, by reducing aqueous humor secretion. Elevated intraocular pressure is a major risk factor in the pathogenesis of optic nerve…

Clinical Trials (5)

NCT02325518Phase 4Completed

Comparison of Intraocular Pressure (IOP)-Lowering Efficacy and Safety of AZORGA® Ophthalmic Suspension and COSOPT® Ophthalmic Solution

Started Dec 2014
218 enrolled
Open-Angle GlaucomaOcular Hypertension
NCT01471158Phase 4Completed

Patient Preference Comparison of AZARGA Versus COSOPT in Patients With Glaucoma

Started Sep 2010
NCT01111890Phase 4Completed

Comparison of the Efficacy of AZARGA® Versus COSOPT® in Patients With Open-Angled Glaucoma or Ocular Hypertension

Started Apr 2010
70 enrolled
GlaucomaOcular Hypertension
NCT00957190Phase 4Completed

The DIOXXACT Trial(Diurnal IOP and OBF Xalatan vs Xalatan And Cosopt Trial)

Started May 2009
25 enrolled
Eye Disease
NCT00832377Phase 2Completed

COSOPT (Timolol/Dorzolamide Combination) Normal Tension Glaucoma Study (MK0507A-161)(COMPLETED)

Started Apr 2009
37 enrolled
Glaucoma