NDAOPHTHALMICSOLUTION/DROPS1 Generic Approved
Approved
Apr 1998
Lifecycle
LOE Approaching
Competitive Pressure
45/100
Clinical Trials
13
Data completeness
4/8 — Partial
Drug data last refreshed 14h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
COSOPT is a fixed-dose combination ophthalmic solution containing dorzolamide (carbonic anhydrase inhibitor) and timolol (beta-blocker) for topical eye administration. It is indicated for reducing intraocular pressure in patients with open-angle glaucoma or ocular hypertension. The dual mechanism provides synergistic IOP reduction by decreasing aqueous humor production through two independent pathways.
$0.135MPart D
LOE ApproachingDeclining
Product nearing loss of exclusivity with minimal Part D volume signals a contracting commercial footprint and likely reduced team investment.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (13)
Comparison of Intraocular Pressure (IOP)-Lowering Efficacy and Safety of AZORGA® Ophthalmic Suspension and COSOPT® Ophthalmic Solution
Started Dec 2014
218 enrolled
Open-Angle GlaucomaOcular Hypertension
Patient Preference Comparison of AZARGA Versus COSOPT
Started Sep 2011
112 enrolled
Open-Angle GlaucomaOcular Hypertension
Patient Preference Comparison of AZARGA Versus COSOPT in Patients With Glaucoma
Started Sep 2010
120 enrolled
Glaucoma
Comparison of the Efficacy of AZARGA® Versus COSOPT® in Patients With Open-Angled Glaucoma or Ocular Hypertension
Started Apr 2010
70 enrolled
GlaucomaOcular Hypertension
The DIOXXACT Trial(Diurnal IOP and OBF Xalatan vs Xalatan And Cosopt Trial)
Started May 2009
25 enrolled
Eye Disease
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.