CORTISPORIN

LOE Approaching

hydrocortisone; neomycin sulfate; polymyxin b sulfate

NDAOPHTHALMICSUSPENSION/DROPS
Approved
Dec 1964
Lifecycle
LOE Approaching
Competitive Pressure
30/100

Mechanism of Action

CLINICAL PHARMACOLOGY Colistin sulfate is a polypeptide antibiotic which penetrates into and disrupts the bacterial cell membrane. Neomycin sulfate is an aminoglycoside antibiotic which inhibits protein synthesis, disrupting the normal cycle of ribosomal function. Hydrocortisone acetate is a…