NDAINJECTIONINJECTABLE
Approved
Sep 1957
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
1
Data completeness
4/8 — Partial
CORTICOTROPIN (corticotropin) by Teva is clinical pharmacology purified cortrophin gel is the anterior pituitary hormone which stimulates the functioning adrenal cortex to produce and secrete adrenocortical hormones. First approved in 1957.
Drug data last refreshed 20h ago · AI intelligence enriched 1mo ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Corticotropin is a purified anterior pituitary hormone administered by intramuscular injection that stimulates the adrenal cortex to produce and secrete adrenocortical hormones. It reaches peak cortisol concentration within 8 hours of a single 80-unit dose. The drug is indicated for patients requiring adrenocortical stimulation.
LOE Approaching
This legacy injectable faces LOE pressure with moderate competitive intensity (30/100); brand team likely focused on transition planning rather than expansion.
Mechanism of Action
CLINICAL PHARMACOLOGY Purified Cortrophin Gel is the anterior pituitary hormone which stimulates the functioning adrenal cortex to produce and secrete adrenocortical hormones. Following administration of a single intramuscular injection of 80 Units of Cortrophin Gel to healthy volunteers (n=20) in…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (1)
Dose Response Relationship for Single Doses of Corticotropin Releasing Hormone (CRH) in Normal Volunteers and in Patients With Adrenal Insufficiency
Started Mar 1982
2,250 enrolled
Adrenal Gland HyperfunctionAdrenal Gland HypofunctionCushing's Syndrome+1 more
Why This Matters for Your Career
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.