NDAINTRAVENOUSSOLUTION
Approved
Jan 2017
Lifecycle
Peak
Competitive Pressure
30/100
Clinical Trials
1
Data completeness
4/8 — Partial
CORPHEDRA (ephedrine sulfate) by Pfizer is α- and ß adrenergic receptors and indirectly causes the release of norepinephrine from sympathetic neurons. First approved in 2017.
Drug data last refreshed 10h ago · AI intelligence enriched 17h ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
CORPHEDRA (ephedrine sulfate) is an IV sympathomimetic amine that activates α- and β-adrenergic receptors while indirectly releasing norepinephrine from sympathetic neurons. It is used to restore and maintain blood pressure in perioperative hypotension by increasing arterial pressure, cardiac output, and peripheral resistance. The drug is indicated for patients experiencing hemodynamic instability in acute care settings.
Peak
Product is at peak commercial maturity with moderate competitive pressure (30); team focus is on defending market position and optimizing hospital/perioperative channel penetration.
Mechanism of Action
α- and ß adrenergic receptors and indirectly causes the release of norepinephrine from sympathetic neurons. Pressor effects by direct alpha- and beta-adrenergic receptor activation are mediated by increases in arterial pressures, cardiac output, and peripheral resistance. Indirect adrenergic…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (1)
Bioequivalence Study of Desloratadine and Pseudoephedrine Sulfate Extended-release Tablets Under Fasting Conditions
Started Apr 2006
34 enrolled
Healthy
Career Relevance
CORPHEDRA has zero linked job openings in current pharma job markets, indicating a mature, stable team with limited turnover or expansion. Working on this product offers deep expertise in hospital-based acute care sales and sympathomimetic pharmacology, but limited upward mobility unless the product enters a growth or LOE transition phase.
Hospital Account Manager
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.