NDATOPICALLOTION
Approved
Mar 1963
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
CORDRAN (flurandrenolide) by Molecular Devices is clinical pharmacology cordran is primarily effective because of its anti-inflammatory, antipruritic, and vasoconstrictive actions. Approved for corticosteroid [epc]. First approved in 1963.
Drug data last refreshed 2h ago · AI intelligence enriched 6d ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
CORDRAN (flurandrenolide) is a topical corticosteroid lotion approved in 1963 for inflammatory and pruritic skin conditions. It works by stabilizing cellular and lysosomal membranes to reduce inflammation, suppress immune response, and provide vasoconstrictive effects. The drug is absorbed through the skin and metabolized hepatically before renal excretion.
LOE Approaching
This established product with low current spending (~$3M annually) is approaching loss of exclusivity, signaling a mature commercial team focused on defending share against generics rather than growth.
Mechanism of Action
CLINICAL PHARMACOLOGY Cordran is primarily effective because of its anti-inflammatory, antipruritic, and vasoconstrictive actions. The mechanism of the anti-inflammatory effect of topical corticosteroids is not completely understood. Corticosteroids with anti-inflammatory activity may stabilize…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.