NDAINJECTIONINJECTABLEPriority Review
Approved
Aug 1962
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
2/8 — Basic
Priority Review
CONRAY 43 (iothalamate meglumine) by Guerbet is clinical pharmacology following intravascular injection, conray is rapidly transported through the circulatory system to the kidneys and is excreted unchanged in the urine by glomerular filtration. First approved in 1962.
Drug data last refreshed 10h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
CONRAY 43 is an iodinated contrast agent containing iothalamate meglumine, used for radiographic visualization in angiography, urography, and CT imaging. The drug is rapidly distributed through the circulatory system and excreted unchanged via glomerular filtration, allowing real-time imaging of vascular and organ structures. It crosses the blood-brain barrier minimally, making it suitable for intracranial CT enhancement.
LOE Approaching
As a legacy diagnostic contrast agent approaching loss of exclusivity, the CONRAY 43 brand team is likely focused on cost management and defending market share against generic competition rather than growth initiatives.
Mechanism of Action
CLINICAL PHARMACOLOGY Following intravascular injection, Conray is rapidly transported through the circulatory system to the kidneys and is excreted unchanged in the urine by glomerular filtration. The pharmacokinetics of intravascularly administered radiopaque contrast media are usually best…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.