CONRAY 400
LOE Approachingiothalamate sodium
NDAINJECTIONINJECTABLE
Approved
Sep 1963
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
2/8 — Basic
CONRAY 400 (iothalamate sodium) is clinical pharmacology the renal clearance of sodium iothalamate in man closely approximates that of inulin. First approved in 1963.
Drug data last refreshed 5d ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
CONRAY 400 is a sodium iothalamate injection approved in 1963 for diagnostic imaging applications. It functions as a radiopharmaceutical agent that is cleared by glomerular filtration, making it useful for renal function assessment and imaging studies. The compound approximates inulin clearance kinetics with minimal tubular interaction.
LOE Approaching
As a legacy diagnostic agent approaching loss of exclusivity, the brand team is likely focused on retention and operational efficiency rather than growth initiatives.
Mechanism of Action
CLINICAL PHARMACOLOGY The renal clearance of sodium iothalamate in man closely approximates that of inulin. The compound is cleared by glomerular filtration without tubular secretion or reabsorption. Following infusion administration of I-125 iothalamate, the effective half-life is about 0.07 days.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
CONRAY 400 offers limited career expansion opportunities given its mature status and approaching loss of exclusivity. Roles available focus on protecting market share and managing operational efficiency rather than driving innovation or market growth.
Product Manager
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.