NDATRANSDERMALFILM, EXTENDED RELEASE
Approved
Aug 1998
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
5/8 — Partial
COMBIPATCH (estradiol/norethindrone acetate transdermal system) by Noven Pharmaceuticals is estrogen receptor agonists [moa]. Approved for a woman with a uterus for: treatment of moderate to severe vasomotor symptoms due to menopause. First approved in 1998.
Drug data last refreshed 43m ago · AI intelligence enriched 3h ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
COMBIPATCH is a transdermal film delivering estradiol and norethindrone acetate for moderate to severe vasomotor symptoms (hot flashes, night sweats) in menopausal women with an intact uterus. It functions as an estrogen receptor agonist, replacing declining hormones during menopause. The combination of estrogen and progestin protects the endometrium while alleviating vasomotor symptoms.
$5.0MPart D
LOE ApproachingProduct is in late-stage lifecycle with modest Part D utilization; brand team focus will shift toward retention and lifecycle extension strategies as LOE approaches.
Mechanism of Action
Estrogen Receptor Agonists
Pharmacologic Class:
Estrogen
Career Relevance
Working on COMBIPATCH offers stability in operational and manufacturing roles with 8 linked positions, but limited upside in commercial or medical affairs due to LOE proximity. This product is ideal for professionals seeking manufacturing expertise or stable execution roles rather than growth-stage innovation opportunities.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.