COLGATE TOTAL
LOE Approachingsodium fluoride; triclosan
NDADENTALPASTE
Approved
Jul 1997
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
2/8 — Basic
COLGATE TOTAL (sodium fluoride; triclosan). Approved for reduce plaque, gingivitis helps control plaque bacteria, an early form of gum disease and 1 more indications. First approved in 1997.
Drug data last refreshed 5d ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Colgate Total is an over-the-counter dental paste combining sodium fluoride and triclosan to reduce plaque, control plaque bacteria, and treat gingivitis and bleeding gums. It is a topical oral hygiene product applied directly to teeth via brushing. The fluoride strengthens enamel while triclosan provides antimicrobial action against oral pathogens.
LOE Approaching
With LOE approaching and moderate competitive pressure (30), brand teams are likely shifting focus toward line extensions, formulation innovation, and cost management rather than growth investments.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.