NDADENTALPASTE
Approved
Jul 1997
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
COLGATE TOTAL (sodium fluoride; triclosan) by Colgate Palmolive. Approved for reduce plaque, gingivitis helps control plaque bacteria, an early form of gum disease and 1 more indications. First approved in 1997.
Drug data last refreshed 17h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Colgate Total is a fluoride-based toothpaste containing sodium fluoride and triclosan indicated for reducing plaque, controlling plaque bacteria, and managing early-stage gum disease and bleeding gums. It is an over-the-counter dental paste formulation that has been a category standard since 1997. The product works through fluoride's enamel-strengthening action combined with triclosan's antimicrobial properties to prevent oral disease.
LOE Approaching
As a mature OTC product approaching loss of exclusivity, the brand team is likely focused on line extensions, reformulations, and geographic expansion rather than growth-phase hiring.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.