COLGATE TOTAL
LOE Approachingsodium fluoride; triclosan
NDADENTALPASTE
Approved
Jul 1997
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
2/8 — Basic
COLGATE TOTAL (sodium fluoride; triclosan). Approved for reduce plaque, gingivitis helps control plaque bacteria, an early form of gum disease and 1 more indications. First approved in 1997.
Drug data last refreshed 8h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Colgate Total is a dual-active toothpaste containing sodium fluoride and triclosan, designed to reduce plaque, control plaque bacteria, and manage gingivitis and bleeding gums. It is an over-the-counter oral care product administered as a paste via dental route. The formulation leverages fluoride's remineralization properties and triclosan's antimicrobial action to address early-stage gum disease.
LOE Approaching
As an OTC product approaching LOE with moderate competitive pressure (30/100), brand teams face shrinking margins and require strategic repositioning or line extension innovation to sustain relevance.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.