COLD CAPSULE IV
LOE Approachingchlorpheniramine maleate; phenylpropanolamine hydrochloride
NDAORALCAPSULE, EXTENDED RELEASE
Approved
Apr 1985
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
2/8 — Basic
COLD CAPSULE IV (chlorpheniramine maleate; phenylpropanolamine hydrochloride). Approved for these symptoms due to hay fever, other upper respiratory allergies: runny nose itchy, watery eyes sneezing itching of the nose and 1 more indications. First approved in 1985.
Drug data last refreshed 5d ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
COLD CAPSULE IV is an oral extended-release capsule combining chlorpheniramine maleate (a first-generation antihistamine) and phenylpropanolamine hydrochloride (a nasal decongestant) approved in 1985. It treats upper respiratory allergy symptoms including rhinorrhea, pruritus, lacrimation, and pharyngeal irritation associated with hay fever and other allergic conditions. The antihistamine blocks H1 receptors to reduce histamine-mediated vasodilation and mucus secretion, while the decongestant causes vasoconstriction of nasal arterioles.
LOE Approaching
Product is in late-stage lifecycle with competitive pressure at 30%, indicating a contracting market with reduced team investment and promotional activity.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.