COLCRYS

LOE Approaching

colchicine

NDAORALTABLET
Approved
Oct 2009
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
14

Mechanism of Action

elucidated; however, evidence suggests that colchicine may interfere with the intracellular assembly of the inflammasome complex present in neutrophils and monocytes that mediates activation of interleukin-1β. Additionally, colchicine disrupts cytoskeletal functions through inhibition of β-tubulin…

Clinical Trials (5)

NCT06666335Phase 4Not Yet Recruiting

A Study to Evaluate Efficacy and Safety of Anakinra in Chinese Patients With Colchicine-resistent FMF

Started Sep 2025
3 enrolled
Familial Mediterranean Fever (FMF )
NCT06543082Phase 4Recruiting

MACT (Mono Antiplatelet and Colchicine Therapy) Prospective Multicenter Study

Started Aug 2024
490 enrolled
Acute Coronary Syndrome
NCT04516941Phase 3Terminated

CorONa Virus edoxabaN ColchicinE (CONVINCE) COVID-19

Started Jan 2021
60 enrolled
SARS-CoV InfectionCOVID-19
NCT04139655N/AWithdrawn

Colchicine Prevents Myocardial Injury After Non-Cardiac Surgery Pilot Study

Started Sep 2020
0
Myocardial InfarctionMyocardial InjuryMajor Adverse Cardiac Events+1 more
NCT01709981Phase 4Completed

Anti-inflammatory Effects of Colchicine in PCI

Started May 2013
280 enrolled
Coronary Artery Disease