NDAINTRATHECALSOLUTION
Approved
Sep 2017
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
3
Data completeness
4/8 — Partial
CLOROTEKAL (chloroprocaine hydrochloride) by B. Braun is clinical pharmacology chloroprocaine, like other local anesthetics, blocks the generation and the conduction of nerve impulses, presumably by increasing the threshold for electrical excitation in the nerve, by slowing the propagation of the nerve impulse and by reducing the rate of rise of the action potential. First approved in 2017.
Drug data last refreshed 33m ago · AI intelligence enriched 6d ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
CLOROTEKAL (chloroprocaine hydrochloride) is a rapid-onset local anesthetic administered via intrathecal injection that blocks nerve impulse generation and conduction. It is used for regional anesthesia in surgical and procedural settings, with onset typically within 6–12 minutes and duration up to 60 minutes. The drug works by increasing the threshold for electrical excitation in nerves, slowing impulse propagation, and reducing action potential rise rate.
Peak7.5 years to LOE
Product is at peak commercialization stage with stable market positioning; team size likely optimized for maintenance rather than expansion.
Mechanism of Action
CLINICAL PHARMACOLOGY Chloroprocaine, like other local anesthetics, blocks the generation and the conduction of nerve impulses, presumably by increasing the threshold for electrical excitation in the nerve, by slowing the propagation of the nerve impulse and by reducing the rate of rise of the…
Worked on CLOROTEKAL at B. Braun? Share your interview experience or compensation data (+7 days Pro)
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.