NDATOPICALCREAM
Approved
Aug 1977
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
CLODERM (clocortolone pivalate) by Enterprise Therapeutics is clinical pharmacology topical corticosteroids share anti-inflammatory, antipruritic and vasoconstrictive actions. First approved in 1977.
Drug data last refreshed 18h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
CLODERM (clocortolone pivalate) is a topical corticosteroid cream approved in 1977 for inflammatory and pruritic dermatologic conditions. It works through anti-inflammatory, antipruritic, and vasoconstrictive mechanisms that reduce skin inflammation and itching. The drug is absorbed through intact or compromised skin and metabolized hepatically, with excretion via kidneys and bile.
$0.031BPart D
LOE ApproachingProduct is in late-stage maturity with minimal Medicare spending ($31K in 2023), signaling a mature, small-team commercial operation focused on maintenance rather than growth.
Mechanism of Action
CLINICAL PHARMACOLOGY Topical corticosteroids share anti-inflammatory, antipruritic and vasoconstrictive actions. The mechanism of anti-inflammatory activity of the topical corticosteroids is unclear. Various laboratory methods, including vasoconstrictor assays, are used to compare and predict…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.