NDAINJECTIONINJECTABLE
Approved
Oct 1972
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
4
Mechanism of Action
Mechanism of Action Clindamycin inhibits bacterial protein synthesis by binding to the 23S RNA of the 50S subunit of the ribosome. Clindamycin is bacteriostatic.
Indications (15)
the treatment of serious infections caused by susceptible anaerobic bacteriathe treatment of serious infections due to susceptible strains of streptococcipneumococcistaphylococcithe treatment of serious infections caused by susceptible strains of the designated organisms in the conditions listed below: Lower respiratory tract infections including pneumoniaempyemalung abscess caused by anaerobesStreptococcus pneumoniaeother streptococci (except Edevelopment of drug-resistant bacteriamaintain the effectiveness of CLEOCIN PHOSPHATEother antibacterial drugsCLEOCIN PHOSPHATE should be used only to treatprevent infectionsstrongly suspected to be caused by susceptible bacteria
Clinical Trials (4)
Clindamycin Phosphate, Adapalene, and Benzoyl Peroxide Triple Combination Gel in Canadian Patients With Acne Vulgaris
Started Oct 2025
200 enrolled
Acne Vulgaris
Perimenstrual Acne With Clindamycin Phosphate and Benzoyl Peroxide
Started Jan 2017
22 enrolled
Actinic Keratosis
A Efficacy and Safety of Duac™Compared With Clindamycin Phosphate Gel in the Treatment of Mild to Moderate Acne Vulgaris
Started Apr 2013
1,018 enrolled
Acne Vulgaris
W0265-104: A Single-Center, Evaluator-Blinded, Randomized, Placebo-Controlled, Phase 1 Clinical Trial Evaluating the Photoallergic Potential of Topically Applied Clindamycin Phosphate 1.0% and Tretinoin 0.025% (CT Gel) in Healthy Volunteers
Started Nov 2008
64 enrolled
Acne Vulgaris