CLARINEX D 24 HOUR

LOE Approaching

desloratadine; pseudoephedrine sulfate

NDAORALTABLET, EXTENDED RELEASE
Approved
Mar 2005
Lifecycle
LOE Approaching
Competitive Pressure
30/100

Mechanism of Action

long-acting tricyclic histamine antagonist with selective H 1 -receptor histamine antagonist activity. Receptor binding data indicates that at a concentration of 2 to 3 ng/mL (7 nanomolar), desloratadine shows significant interaction with the human histamine H 1 -receptor. Desloratadine inhibited…