NDAINJECTIONINJECTABLEPriority Review
Approved
Nov 1965
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
2/8 — Basic
Priority Review
CITANEST (prilocaine hydrochloride) by AstraZeneca is mechanism of action prilocaine stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses, thereby effecting local anesthetic action. First approved in 1965.
Drug data last refreshed 20h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
CITANEST (prilocaine hydrochloride) is a local anesthetic injectable that stabilizes neuronal membranes to inhibit ionic fluxes required for impulse initiation and conduction. It is used for local and regional anesthesia in surgical and dental procedures. The product targets patients requiring rapid-onset, intermediate-duration local anesthesia.
LOE Approaching
Product approaching loss of exclusivity with moderate competitive pressure (30) signals defensive positioning and likely team consolidation or focus on retained niche segments.
Mechanism of Action
Mechanism of Action Prilocaine stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses, thereby effecting local anesthetic action.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Zero linked job openings and LOE-approaching lifecycle indicate this product offers minimal career growth or advancement opportunity. Professionals evaluating this role should expect defensive commercial activities, cost management focus, and potential role elimination post-LOE rather than expansion or innovation-driven work.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.