CIPRO
LOE ApproachingNDAINJECTIONINJECTABLE
Approved
Dec 1990
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20
Data completeness
4/8 — Partial
CIPRO by Bayer is [see microbiology (12. Approved for infections caused by susceptible isolates of the designated microorganisms in the specific conditions listed below: • acute otitis media (aom) in pediatric patients (age 6 months, older) with tympanostomy tubes due to staphylococcus aureus, streptococcus pneumoniae and 3 more indications. First approved in 1990.
Drug data last refreshed 6h ago · AI intelligence enriched 1mo ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Cipro (ciprofloxacin) is a fluoroquinolone antibiotic that works by inhibiting bacterial DNA gyrase, disrupting bacterial cell division. It treats a broad range of infections including respiratory, urinary, skin, joint, and sexually transmitted infections, as well as bioterrorism-related exposures like plague and anthrax. Cipro is available in injectable formulation with ~70% oral bioavailability and wide tissue distribution, particularly in genital and respiratory tissues.
LOE Approaching
Product approaching loss of exclusivity with established generic competition; expect downsizing of commercial infrastructure and shift to specialty or indication-specific strategies.
Mechanism of Action
[see Microbiology (12.4)] . Dexamethasone, a corticosteroid, has been shown to suppress inflammation by inhibiting multiple inflammatory cytokines resulting in decreased edema, fibrin deposition, capillary leakage and migration of inflammatory cells.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.