NDAOPHTHALMICSOLUTION/DROPS1 Generic Approved
Approved
Dec 1990
Lifecycle
LOE Approaching
Competitive Pressure
45/100
Data completeness
5/8 — Partial
CILOXAN (ciprofloxacin hydrochloride) by Novartis is clinical pharmacology systemic absorption a systemic absorption study was performed in which ciprofloxacin ophthalmic solution was administered in each eye every two hours while awake for two days followed by every four hours while awake for an additional 5 days. Approved for mycobacterium avium complex infection, hiv infections. First approved in 1990.
Drug data last refreshed Yesterday · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
CILOXAN is a fluoroquinolone antibiotic ophthalmic solution containing ciprofloxacin hydrochloride. It treats bacterial eye infections by inhibiting DNA gyrase, a bacterial enzyme essential for DNA synthesis. The drug is bactericidal against a broad spectrum of gram-positive and gram-negative organisms with minimal systemic absorption.
$0.001BPart D
LOE ApproachingProduct is approaching loss of exclusivity with modest Part D spending of $1M and 5,169 claims in 2023, indicating a mature established product with a small stable team.
Mechanism of Action
CLINICAL PHARMACOLOGY Systemic Absorption A systemic absorption study was performed in which ciprofloxacin ophthalmic solution was administered in each eye every two hours while awake for two days followed by every four hours while awake for an additional 5 days. The maximum reported plasma…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.