NDAINJECTIONINJECTABLE
Approved
May 1987
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
CHROMIC CHLORIDE (chromic chloride) by Bristol Myers Squibb is clinical pharmacology trivalent chromium is part of glucose tolerance factor, an essential activator of insulin-mediated reactions. Approved for depletion of endogenous stores, subsequent deficiency symptoms. First approved in 1987.
Drug data last refreshed 12h ago · AI intelligence enriched 6d ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Chromic Chloride is an injectable trace mineral supplement containing trivalent chromium, an essential cofactor for glucose tolerance factor and insulin-mediated reactions. It is indicated for prevention and treatment of chromium deficiency in patients receiving total parenteral nutrition (TPN), preventing symptoms such as impaired glucose tolerance, ataxia, peripheral neuropathy, and encephalopathy-like confusion. Chromium normalizes glucose metabolism and peripheral nerve function by enhancing insulin signaling.
LOE Approaching
Product is approaching loss of exclusivity with moderate competitive pressure (30/100), indicating potential downsizing of brand team and transition focus to generic defense or cost-containment strategies.
Mechanism of Action
CLINICAL PHARMACOLOGY Trivalent chromium is part of glucose tolerance factor, an essential activator of insulin-mediated reactions. Chromium helps to maintain normal glucose metabolism and peripheral nerve function. Providing chromium during TPN helps prevent deficiency symptoms including impaired…
Indications (2)
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.