CHORIONIC GONADOTROPIN
LOE Approachinggonadotropin, chorionic
BLAINJECTIONINJECTABLE
Approved
Mar 1974
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
4
Data completeness
4/8 — Partial
CHORIONIC GONADOTROPIN (gonadotropin, chorionic) is clinical pharmacology: the action of hcg is virtually identical to that of pituitary lh, although hcg appears to have a small degree of fsh activity as well. First approved in 1974.
Drug data last refreshed 12h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Chorionic gonadotropin (HCG) is a naturally occurring hormone approved since 1974 that mimics luteinizing hormone (LH) to stimulate gonadal steroid production in both males and females. It is administered via injection to treat infertility, hypogonadism, and cryptorchidism by promoting testosterone production in males and progesterone support in females. The drug works by stimulating Leydig cells in the testes and the corpus luteum in the ovary, with no effect on fat metabolism or appetite.
$0.565MPart D
LOE ApproachingProduct is in late-stage lifecycle with modest Part D spending ($565K in 2023) and 624 annual claims, indicating a niche market with limited team expansion opportunities.
Mechanism of Action
CLINICAL PHARMACOLOGY: The action of HCG is virtually identical to that of pituitary LH, although HCG appears to have a small degree of FSH activity as well. It stimulates production of gonadal steroid hormones by stimulating the interstitial cells (Leydig cells) of the testis to produce androgens…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (4)
Comparative Bioavailability Study of Human Chorionic Gonadotropin (hCG)-IBSA Versus a Marketed hCG Formulation
Started Nov 2018
26 enrolled
Infertility
A Randomised Trial Using Highly Purified Human Chorionic Gonadotropin (HP-hCG) and Recombinant Human Chorionic Gonadotropin (rhCG) in Women Undergoing Controlled Ovarian Stimulation
Started Apr 2016
176 enrolled
Infertility
Administration of Follicle-stimulating Hormone (FSH) and Low Dose Human Chorionic Gonadotropin (hCG) for Oocyte Maturity While Decreasing hCG Exposure in In Vitro Fertilization (IVF) Cycles
Started Sep 2014
105 enrolled
Infertility
HCG (Human Chorionic Gonadotropin) Priming for Thin Endometrium in IVF (in Vitro Fertilization)
Started Jan 2012
15 enrolled
Endometrial ThicknessPregnancy Outcome
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.