CHORIONIC GONADOTROPIN
LOE Approachinggonadotropin, chorionic
BLAINJECTIONINJECTABLE
Approved
Mar 1974
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
4
Data completeness
4/8 — Partial
CHORIONIC GONADOTROPIN (gonadotropin, chorionic) is clinical pharmacology: the action of hcg is virtually identical to that of pituitary lh, although hcg appears to have a small degree of fsh activity as well. First approved in 1974.
Drug data last refreshed 10h ago · AI intelligence enriched 5d ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Chorionic Gonadotropin (hCG) is a hormone replacement injectable approved in 1974 that mimics luteinizing hormone (LH) to stimulate gonadal steroid production. It is used to treat infertility, hypogonadism, and cryptorchidism by promoting androgen and progesterone synthesis. The drug works by stimulating Leydig cells in males and the corpus luteum in females, with no effect on fat metabolism or appetite.
$0.565MPart D
LOE ApproachingLate-lifecycle product with modest Part D utilization (624 claims, $565K annually) signals a stable but small commercial footprint with limited team expansion opportunity.
Mechanism of Action
CLINICAL PHARMACOLOGY: The action of HCG is virtually identical to that of pituitary LH, although HCG appears to have a small degree of FSH activity as well. It stimulates production of gonadal steroid hormones by stimulating the interstitial cells (Leydig cells) of the testis to produce androgens…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (4)
Comparative Bioavailability Study of Human Chorionic Gonadotropin (hCG)-IBSA Versus a Marketed hCG Formulation
Started Nov 2018
26 enrolled
Infertility
A Randomised Trial Using Highly Purified Human Chorionic Gonadotropin (HP-hCG) and Recombinant Human Chorionic Gonadotropin (rhCG) in Women Undergoing Controlled Ovarian Stimulation
Started Apr 2016
176 enrolled
Infertility
Administration of Follicle-stimulating Hormone (FSH) and Low Dose Human Chorionic Gonadotropin (hCG) for Oocyte Maturity While Decreasing hCG Exposure in In Vitro Fertilization (IVF) Cycles
Started Sep 2014
105 enrolled
Infertility
HCG (Human Chorionic Gonadotropin) Priming for Thin Endometrium in IVF (in Vitro Fertilization)
Started Jan 2012
15 enrolled
Endometrial ThicknessPregnancy Outcome
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.