NDAOPHTHALMICOINTMENT
Approved
Jun 1951
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
CHLOROMYCETIN (chloramphenicol) by Pfizer is clinical pharmacology chloramphenicol is a broad-spectrum antibiotic originally isolated from streptomyces venezuelae . Approved for surface ocular infections involving the conjunctiva and/or cornea caused by chloramphenicol-susceptible organisms. First approved in 1951.
Drug data last refreshed 20h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
CHLOROMYCETIN (chloramphenicol) is a broad-spectrum bacteriostatic antibiotic originally isolated from Streptomyces venezuelae, approved in 1951 for ophthalmic use. It treats surface ocular infections of the conjunctiva and cornea by inhibiting bacterial protein synthesis through interference with amino acid transfer to ribosomes. The drug is formulated as an ophthalmic ointment with minimal resistance development in susceptible organisms.
LOE Approaching
With LOE approaching and no Part D spending data, the ophthalmic franchise is likely managed by a lean, specialized team focused on legacy product maintenance rather than growth expansion.
Mechanism of Action
Clinical Pharmacology Chloramphenicol is a broad-spectrum antibiotic originally isolated from Streptomyces venezuelae . It is primarily bacteriostatic and acts by inhibition of protein synthesis by interfering with the transfer of activated amino acids from soluble RNA to ribosomes. It has been…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.