CHIRHOSTIM

LOE Approaching

human secretin

NDAINTRAVENOUSFOR SOLUTIONPriority Review
Approved
Apr 2004
Lifecycle
LOE Approaching
Competitive Pressure
30/100

Mechanism of Action

Mechanism of Action 12.1 Mechanism of Action The primary action of ChiRhoStim is to stimulate pancreatic ductal cells to secrete pancreas fluid in large volumes that contain bicarbonate. Secretin is a hormone that is normally released from the duodenum upon exposure of the proximal intestinal lumen…