CESAMET

LOE Approaching

nabilone

NDAORALCAPSULE
Approved
Dec 1985
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
3

Mechanism of Action

CLINICAL PHARMACOLOGY Pharmacodynamics Cesamet (nabilone) is an orally active synthetic cannabinoid which, like other cannabinoids, has complex effects on the central nervous system (CNS). It has been suggested that the antiemetic effect of nabilone is caused by interaction with the cannabinoid…

Pharmacologic Class:

Cannabinoid

Clinical Trials (3)

NCT00480181Phase 4Completed

Efficacy and Safety Evaluation of Nabilone as Adjunctive Therapy to Gabapentin for the Management of Neuropathic Pain in Multiple Sclerosis

Started Jun 2007
50 enrolled
Neuropathic PainMultiple Sclerosis
NCT00418678Phase 4Terminated

A Phase IV Trial of Cesamet™ Given With Standard Antiemetic Therapy for Chemotherapy-induced Nausea and Vomiting

Started Aug 2006
16 enrolled
Nausea and Vomiting
NCT00384410Phase 2Unknown

Use of the Cannabinoid Nabilone for the Promotion of Sleep in Chronic, Non-Malignant Pain Patients

Started Dec 2005
16 enrolled
PainInsomnia