CELLCEPT

LOE Approaching

mycophenolate mofetil hydrochloride

NDAINJECTIONINJECTABLE
Approved
Aug 1998
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20

Mechanism of Action

(MMF) is absorbed following oral administration and hydrolyzed to mycophenolic acid (MPA), the active metabolite. MPA is a selective uncompetitive inhibitor of the two isoforms (type I and type II) of inosine monophosphate dehydrogenase (IMPDH) leading to inhibition of the de novo pathway of…

Clinical Trials (5)

NCT01014442Phase 3Completed

A Study of Mycophenolate Mofetil (CellCept) in Lung Transplant Recipients

Started Jan 2010
68 enrolled
Lung Transplantation
NCT01707550N/ACompleted

An Observational Study of CellCept (Mycophenolate Mofetil) in Renal Allograft Recipients

Started Dec 2009
414 enrolled
Kidney Transplantation
NCT01033864Phase 4Completed

A Pharmacokinetic Study of CellCept (Mycophenolate Mofetil) Versus Mycophenolate Sodium in Kidney Transplant Patients

Started Nov 2009
23 enrolled
Kidney Transplantation
NCT00991510Phase 4Terminated

Comparative Bioavailability of Myfenax® and CellCept® in Kidney Transplant Patients

Started Aug 2009
43 enrolled
Stable Renal Transplant Recipients
NCT00652834Phase 4Completed

Small Bowel Capsule Endoscopy Findings in Patients Receiving Cellcept®

Started Apr 2009
23 enrolled
Gastrointestinal LesionsSigns and Symptoms, Digestive