CEFIZOX
LOE ApproachingNDAINJECTIONINJECTABLE
Approved
Sep 1983
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
CEFIZOX by Astellas is clinical pharmacology the table below demonstrates the serum levels and duration of cefizox (ceftizoxime for injection, usp) following im administration of 500 mg and 1 gram doses, respectively, to normal volunteers. Approved for the treatment of infections due to susceptible strains of the microorganisms listed below. First approved in 1983.
Drug data last refreshed 1h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Cefizox (ceftizoxime) is a third-generation cephalosporin antibiotic administered by injection for treatment of infections caused by susceptible gram-positive, gram-negative, and anaerobic microorganisms. The drug works by inhibiting bacterial cell-wall synthesis and is highly resistant to beta-lactamase enzymes produced by resistant organisms. It achieves therapeutic levels across multiple body compartments including cerebrospinal fluid, bone, and various tissues, making it suitable for serious systemic and localized infections.
LOE Approaching
Product is in late-stage lifecycle with approaching loss of exclusivity, indicating a consolidating commercial team focused on managed care and retention rather than growth initiatives.
Mechanism of Action
Clinical Pharmacology The table below demonstrates the serum levels and duration of Cefizox (ceftizoxime for injection, USP) following IM administration of 500 mg and 1 gram doses, respectively, to normal volunteers. Serum Concentrations After Intramuscular Administration Serum Concentration…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.