NDAOTICSUSPENSION/DROPS
Approved
May 1975
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
CASPORYN HC (neomycin and polymyxin b sulfates and hydrocortisone otic) by R-Pharm US is corticosteroid hormone receptor agonists [moa]. First approved in 1975.
Drug data last refreshed 20h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
CASPORYN HC is a fixed-dose combination otic suspension containing neomycin and polymyxin B sulfates (antibiotics) plus hydrocortisone (corticosteroid) for topical ear use. It treats bacterial ear infections with associated inflammation by combining broad-spectrum antimicrobial activity with anti-inflammatory corticosteroid effects. The hydrocortisone acts as a corticosteroid hormone receptor agonist to reduce swelling and discomfort.
LOE Approaching
This vintage 1975 product faces LOE pressure and moderate competitive intensity (30/100), suggesting shrinking team resources and defensive marketing strategy.
Mechanism of Action
Corticosteroid Hormone Receptor Agonists
Pharmacologic Class:
Corticosteroid
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Working on CASPORYN HC offers limited career growth potential given its approaching LOE, vintage profile, and zero linked job openings. This assignment is typically defensive work—maintaining market share and managing the transition to generic competition—rather than driving innovation or expansion.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.