NDAOTICSUSPENSION/DROPS
Approved
May 1975
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
CASPORYN HC (neomycin and polymyxin b sulfates and hydrocortisone otic) by R-Pharm US is corticosteroid hormone receptor agonists [moa]. First approved in 1975.
Drug data last refreshed 19h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
CASPORYN HC is a fixed-combination otic suspension containing neomycin and polymyxin B sulfates (antibiotics) plus hydrocortisone (corticosteroid) for topical ear use. It treats bacterial ear infections with inflammatory components by combining antimicrobial activity with anti-inflammatory steroid action. The hydrocortisone component acts as a corticosteroid hormone receptor agonist to reduce swelling and discomfort.
LOE Approaching
This product faces LOE headwinds with moderate competitive pressure (30/100) and minimal linked job activity, suggesting a mature, contracted portfolio assignment with limited expansion opportunities.
Mechanism of Action
Corticosteroid Hormone Receptor Agonists
Pharmacologic Class:
Corticosteroid
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Working on CASPORYN HC offers limited career upside as a mature, losing-exclusivity otic product with zero linked job openings. This role is typically a maintenance assignment focused on cost management, generic transition planning, and customer retention rather than growth and innovation.
Brand Manager (Mature/Maintenance)
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.