NDAORALTABLET2 Generics Approved
Approved
Nov 1982
Lifecycle
LOE Approaching
Competitive Pressure
60/100
Data completeness
2/8 — Basic
Drug data last refreshed 3d ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
CARDIZEM (diltiazem hydrochloride) is an oral calcium channel blocker tablet approved in 1982 for hypertension treatment. It works by inhibiting calcium ion influx during cardiac and vascular smooth muscle depolarization, resulting in vascular smooth muscle relaxation and decreased peripheral vascular resistance. The drug produces antihypertensive effects without reflex tachycardia and has demonstrated efficacy in reducing coronary artery spasm.
LOE Approaching
Product faces LOE and moderate competitive pressure (60%) from newer ARBs and combination therapies; team likely prioritizing retention and lifecycle management rather than growth initiatives.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Working on CARDIZEM offers limited career growth in a mature, LOE-approaching product with minimal linked job openings and declining commercial momentum. Roles focus on defensive commercial execution, payer management, and customer retention rather than innovation or market expansion.
Brand ManagerRegional Sales Manager
Worked on CARDIZEM at Bausch + Lomb? Share your interview experience or compensation data (+7 days Pro)
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.