NDAORALTABLET3 Generics Approved
Approved
Nov 1982
Lifecycle
LOE Approaching
Competitive Pressure
60/100
Data completeness
2/8 — Basic
Drug data last refreshed 36m ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
CARDIZEM (diltiazem hydrochloride) is a calcium channel blocker oral tablet approved in 1982 for cardiovascular indications including hypertension and angina. It works by inhibiting calcium influx into vascular smooth muscle and cardiac cells, resulting in vasodilation and reduced cardiac workload. This small molecule has become a cornerstone therapy in cardiology with decades of clinical use.
LOE Approaching
With LOE approaching and 60% competitive pressure, the brand team is likely consolidating resources toward niche segments and preparing for generic transition, signaling potential team restructuring and reduced headcount growth.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Working on CARDIZEM at LOE stage offers limited growth trajectory but provides stability in a managed-decline environment; roles emphasize customer retention, payer negotiations, and cost-of-goods optimization rather than market expansion. Career advancement may be constrained due to reduced headcount and budget allocation.
Brand ManagerField Sales Representative
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.