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Upgrade to Pro — $25/moCARBOPLATIN (carboplatin) by Fresenius Kabi is clinical pharmacology carboplatin, like cisplatin, produces predominantly inter strand dna cross-links rather than dna-protein cross-links. Approved for for the initial treatment of advanced ovarian carcinoma. First approved in 2012.
Drug data last refreshed 18h ago
CLINICAL PHARMACOLOGY Carboplatin, like cisplatin, produces predominantly inter strand DNA cross-links rather than DNA-protein cross-links. This effect is apparently cell-cycle nonspecific. The aquation of carboplatin, whichis thought to produce the active species, occurs at a slower rate than in…
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