NDAINJECTIONINJECTABLEPriority Review
Approved
May 1960
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
2/8 — Basic
Priority Review
CARBOCAINE (mepivacaine hydrochloride) by Pfizer is clinical pharmacology mepivacaine hydrochloride is a potent local anesthetic whose effectiveness and safety have been well established in human medicine and dentistry. First approved in 1960.
Drug data last refreshed 3h ago · AI intelligence enriched 3w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Carbocaine (mepivacaine hydrochloride) is a potent local anesthetic injectable with efficacy 2–2.5× that of procaine and comparable to lidocaine. It produces rapid, marked local anesthesia lasting several hours, enabling prolonged surgical procedures in veterinary medicine. The drug's vasoconstrictive activity can be enhanced with epinephrine addition for extended duration.
LOE Approaching
Product approaching loss of exclusivity with moderate competitive pressure (30%); brand team likely focused on cost management and market retention rather than growth initiatives.
Mechanism of Action
CLINICAL PHARMACOLOGY Mepivacaine hydrochloride is a potent local anesthetic whose effectiveness and safety have been well established in human medicine and dentistry. Laboratory and clinical studies in animals have confirmed its value in veterinary medicine. Its anesthetic activity is two to two…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Working on Carbocaine means operating in a stable, mature market with zero linked job openings currently, reflecting minimal team growth or expansion. Career progression depends on cost optimization, market retention, and maintaining veterinary practitioner relationships rather than new product launches or market expansion.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.