CARBAMAZEPINE

Post-LOE

carbamazepine

ANDAORALCAPSULE, EXTENDED RELEASE
Approved
May 2011
Lifecycle
Post-LOE
Competitive Pressure
30/100
Clinical Trials
20

Mechanism of Action

Mechanism of Action Carbamazepine has demonstrated anticonvulsant properties in rats and mice with electrically and chemically induced seizures. It appears to act by reducing polysynaptic responses and blocking the post-tetanic potentiation. Carbamazepine greatly reduces or abolishes pain induced…

Clinical Trials (5)

NCT07446400Phase 1Not Yet Recruiting

A Trial to Examine the Interaction of Repinatrabit With Ethinyl Estradiol/Norethindrone, Metformin,Carbamazepine, Rosuvastatin, and Methotrexate When Administered Together

Started Mar 2026
48 enrolled
Healthy Volunteers
NCT07395024Phase 1Recruiting

A Study to Learn How Fluconazole, Carbamazepine and Itraconazole Affect How the Body Processes ASP3082 in Healthy Adults

Started Feb 2026
54 enrolled
Healthy Volunteer
NCT07279233Phase 1Not Yet Recruiting

To Assess the Enzyme Inducing Effects of Carbamazepine on the PK of Mirdametinib in Healthy Participants

Started Dec 2025
36 enrolled
HealthyVolunteer
NCT07198035Phase 1Recruiting

A Study to Learn if Multiple Doses of the Study Medicine Called Carbamazepine Changes How the Body Processes the Other Study Medicine PF-07248144

Started Sep 2025
12 enrolled
Healthy Adults
NCT07100964Phase 1Completed

A Study in Healthy Men to Test Whether Carbamazepine Influences the Amount of Nerandomilast in the Blood

Started Aug 2025
16 enrolled
Healthy