NDAORALTABLETPriority Review
Approved
Oct 1981
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
4/8 — Partial
Priority Review
CARAFATE (sucralfate) by AbbVie is clinical pharmacology sucralfate is only minimally absorbed from the gastrointestinal tract. First approved in 1981.
Drug data last refreshed 1m ago · AI intelligence enriched 2d ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
CARAFATE (sucralfate) is an oral aluminum complex that accelerates healing of duodenal ulcers through local cytoprotective action. It forms an ulcer-adherent complex that protects the ulcer site from acid, pepsin, and bile salts while minimally being absorbed systemically. The mechanism involves barrier formation, pepsin inhibition, and bile salt adsorption at the ulcer site.
$0.002BPart D
LOE ApproachingDeclining
Product is approaching loss of exclusivity with modest Part D spending ($2M), signaling a mature, stable franchise with limited growth opportunities and likely contracted team infrastructure.
Mechanism of Action
CLINICAL PHARMACOLOGY Sucralfate is only minimally absorbed from the gastrointestinal tract. The small amounts of the sulfated disaccharide that are absorbed are excreted primarily in the urine. Although the mechanism of sucralfate's ability to accelerate healing of duodenal ulcers remains to be…
Pharmacologic Class:
Aluminum Complex
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.