CARAC
LOE Approachingfluorouracil cream, 0.5%
NDATOPICALCREAM
Approved
Oct 2000
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
1
Data completeness
5/8 — Partial
CARAC (fluorouracil cream, 0.5%) is nucleic acid synthesis inhibitors [moa]. First approved in 2000.
Drug data last refreshed 4d ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
CARAC is a topical cream formulation of fluorouracil 0.5% approved in 2000 for treatment of actinic keratosis and other skin conditions. It works by inhibiting nucleic acid synthesis, disrupting DNA and RNA production in rapidly dividing cells. The drug is administered as a topical application directly to affected skin areas.
$0.049MPart D
LOE ApproachingProduct approaching loss of exclusivity with minimal current Part D volume suggests a defensive or transition-phase commercial operation with limited team growth opportunity.
Mechanism of Action
Nucleic Acid Synthesis Inhibitors
Pharmacologic Class:
Nucleoside Metabolic Inhibitor
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (1)
Carac & PDT Combination in the Treatment Of Actinic Keratoses
Started Aug 2008
60 enrolled
Actinic Keratoses
Career Relevance
CARAC presents a challenging career landscape with zero currently linked job openings and approaching loss of exclusivity, indicating declining commercial investment and team contraction. Career growth on this product is limited; professionals should consider it a maintenance role or stepping stone to higher-growth portfolio assets.
Brand Manager
Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.