NDAORALTABLET
Approved
Oct 1984
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Mechanism of Action
CLINICAL PHARMACOLOGY Mechanism of Action The mechanism of action of captopril has not yet been fully elucidated. Its beneficial effects in hypertension and heart failure appear to result primarily from suppression of the renin-angiotensin-aldosterone system. However, there is no consistent…
Indications (9)
hypertensiondiabetic nephropathy (proteinuria > 500 mg/day) in patients with type I insulin-dependent diabetes mellitusretinopathythe treatment of congestive heart failure usually in combination with diureticsdigitalissurvival following myocardial infarction in clinically stable patients with left ventricular dysfunction manifestedto reduce the incidence of overt heart failuresubsequent hospitalizations for congestive heart failure in these patientsHeart Failure