CAMPATH

LOE ApproachingmAb

alemtuzumab

BLAINTRAVENOUSVIALPriority Review
Approved
May 2001
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20

Mechanism of Action

CD52-directed Antibody Interactions

Pharmacologic Class:

CD52-directed Cytolytic Antibody

Indications (1)

Clinical Trials (5)

NCT05384756Phase 1Active Not Recruiting

TMLI and Alemtuzumab for Treatment of Sickle Cell Disease

Started Jul 2022
NCT03983252Phase 1/2Withdrawn

Effect of Alemtuzumab on Microglial Activation Positron Emission Tomography (PET) in Multiple Sclerosis

Started Dec 2021
0
Multiple Sclerosis
NCT05075499N/AUnknown

Immune Response to COVID-19 Vaccine in Multiple Sclerosis Patients Treated With Teriflunomide and Alemtuzumab

Started Mar 2021
70 enrolled
Multiple Sclerosis
NCT04312841Phase 2Completed

Letermovir for the Prevention of Cytomegalovirus Reactivation in Patients With Hematological Malignancies Treated With Alemtuzumab

Started Sep 2020
6 enrolled
B-Cell Prolymphocytic LeukemiaChronic Lymphocytic LeukemiaPeripheral T-Cell Lymphoma+3 more
NCT03591380Phase 2Terminated

CAMPath and BELimumab for Transplant Tolerance in Sensitized Kidney Transplant Recipients

Started May 2019
3 enrolled
Kidney Transplantation