CADUET

LOE ApproachingSM

amlodipine and atorvastatin

NDAORALTABLET
Approved
Jan 2004
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
8

Mechanism of Action

drugs, a dihydropyridine calcium channel blocker (amlodipine) and an HMG-CoA reductase inhibitor (atorvastatin). The amlodipine component of amlodipine and atorvastatin tablets inhibits the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle. The atorvastatin…

Clinical Trials (5)

NCT01190007Phase 4Completed

Open Label Study To Evaluate The Long-Term Safety Profiles Of Caduet In Japanese Patients

Started Aug 2010
159 enrolled
HypertensionHypercholesterolemiaAngina Pectoris
NCT01107743N/ACompleted

Amlodipine/Atorvastatin (Caduet®) Drug Use Investigation (Regulatory Post Marketing Commitment Plan)

Started Jun 2010
1,291 enrolled
HypertensionAngina PectorisHypercholesterolemia+1 more
NCT00579254N/ATerminated

Real Life Experience With Caduet In Patients With Cardiovascular Risk Factors

Started Dec 2007
112 enrolled
Hypertension and Cardiovascular Risk Factors
NCT00407537Phase 4Completed

Caduet vs Usual Care in Subjects With Hypertension and Additional Risk Factors

Started Mar 2007
1,531 enrolled
HypertensionHypercholesterolemia
NCT00332761Phase 4Completed

Caduet in an Untreated Subject Population

Started Jun 2006
220 enrolled
HypertensionDyslipidemia