CABENUVA KIT

Peak

cabotegravir and rilpivirine

NDAINTRAMUSCULARSUSPENSION, EXTENDED RELEASEPriority Review
Approved
Jan 2021
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
4

Mechanism of Action

2 long-acting HIV-1 antiretroviral drugs, cabotegravir and rilpivirine [see Microbiology ()] .

Clinical Trials (4)

NCT07370649N/ANot Yet Recruiting

Long-Acting Cabotegravir and Rilpivirine in People Living With HIV-1 Subtype A6: A Real-World Retrospective Study

Started Feb 2026
250 enrolled
Human Immunodeficiency Virus (HIV)-1 InfectionHIV-1 Subtype A6 InfectionHIV-1 Subtype B Infection+1 more
NCT04371380Phase 1Completed

Pharmacokinetic Study of Cabotegravir and Rilpivirine Long-acting Intramuscular Injections in Healthy Adult Participants

Started Sep 2020
15 enrolled
HIV Infections
NCT03497676Phase 1/2Completed

More Options for Children and Adolescents (MOCHA): Oral and Long-Acting Injectable Cabotegravir and Rilpivirine in HIV-Infected Children and Adolescents

Started Apr 2019
168 enrolled
HIV Infections
NCT02938520Phase 3Active Not Recruiting

Study to Evaluate the Efficacy, Safety, and Tolerability of Long-acting Intramuscular Cabotegravir and Rilpivirine for Maintenance of Virologic Suppression Following Switch From an Integrase Inhibitor in HIV-1 Infected Therapy Naive Participants

Started Oct 2016
631 enrolled
HIV Infections

Loss of Exclusivity

LOE Date
Jul 18, 2038
150 months away
Patent Expiry
Jul 18, 2038
Exclusivity Expiry
Jan 21, 2026

Patent Records (5)

Patent #ExpiryTypeUse Code
10927129
Apr 28, 2026
SubstanceProduct
11389447
Jun 30, 2027
U-3405
8410103
Feb 4, 2031
SubstanceProduct
U-3348
12138264
Sep 15, 2031
Product
U-3348
11224597
Sep 15, 2031
Product
U-3348