BUTALBITAL, ASPIRIN AND CAFFEINE

Post-LOE

aspirin; butalbital; caffeine

Hikma
ANDAORALTABLET
Approved
Jun 1979
Lifecycle
Post-LOE
Competitive Pressure
30/100

Mechanism of Action

Butalbital, a barbiturate, is a GABA A receptor agonist and may inhibit excitatory AMPA receptors. Aspirin is a nonsteroidal anti-inflammatory drug and a non-selective irreversible inhibitor of cyclooxygenases. Caffeine is a methylxanthine and CNS stimulant. The exact mechanism with respect to the…

Indications (3)

the symptom complex of tension (or muscle contraction) headacheother non-opioid analgesicsalternative treatments are inadequate
Company
Hikma
Hikma
NJ - Berkeley Heights
External Resources
DailyMed
Full prescribing information
FDA Drugs@FDA
FDA approval history
RxNorm
Drug nomenclature & identifiers
Data Sources
  • Drug label: DailyMed / FDA
  • Clinical trials: ClinicalTrials.gov
  • Patent data: FDA Orange Book
  • Spending data: CMS Medicare

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.