BUTALBITAL, ASPIRIN AND CAFFEINE

Pre-Launch

aspirin; butalbital; caffeine

ANDAORALTABLET
Lifecycle
Pre-Launch

Mechanism of Action

Butalbital, a barbiturate, is a GABA A receptor agonist and may inhibit excitatory AMPA receptors. Aspirin is a nonsteroidal anti-inflammatory drug and a non-selective irreversible inhibitor of cyclooxygenases. Caffeine is a methylxanthine and CNS stimulant. The exact mechanism with respect to the…