NDAORALTABLET
Approved
Feb 1983
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
3
Mechanism of Action
CLINICAL PHARMACOLOGY Bumex is a loop diuretic with a rapid onset and short duration of action. Pharmacological and clinical studies have shown that 1 mg Bumex has a diuretic potency equivalent to approximately 40 mg furosemide. The major site of Bumex action is the ascending limb of the loop of…
Pharmacologic Class:
Loop Diuretic
Clinical Trials (3)
Bumetanide vs. Furosemide in Cirrhosis
Started Mar 2026
500 enrolled
Cirrhosis
Pilot Study of Bumetanide for Newborn Seizures
Started Jan 2010
43 enrolled
Seizures
Study to Evaluate the Potential Pharmacokinetic Interaction and Pharmacodynamic Effects on Renal Parameters of Bumetanide (1mg) and Dapagliflozin (10 mg) When Co-administered in Healthy Subjects
Started Jul 2009
42 enrolled
Type 2 Diabetes Mellitus