BUMETANIDE

Post-LOE

bumetanide

ANDAINJECTIONINJECTABLE
Approved
Feb 2026
Lifecycle
Post-LOE
Competitive Pressure
30/100
Clinical Trials
3

Mechanism of Action

CLINICAL PHARMACOLOGY Bumetanide is a loop diuretic with a rapid onset and short duration of action. Pharmacological and clinical studies have shown that 1 mg bumetanide has a diuretic potency equivalent to approximately 40 mg furosemide. The major site of bumetanide action is the ascending limb of…

Pharmacologic Class:

Loop Diuretic

Clinical Trials (3)

NCT06941415Phase 3Not Yet Recruiting

Bumetanide vs. Furosemide in Cirrhosis

Started Mar 2026
500 enrolled
Cirrhosis
NCT00830531Phase 1Completed

Pilot Study of Bumetanide for Newborn Seizures

Started Jan 2010
43 enrolled
Seizures
NCT00930865Phase 1Completed

Study to Evaluate the Potential Pharmacokinetic Interaction and Pharmacodynamic Effects on Renal Parameters of Bumetanide (1mg) and Dapagliflozin (10 mg) When Co-administered in Healthy Subjects

Started Jul 2009
42 enrolled
Type 2 Diabetes Mellitus