BSS PLUS
LOE Approachingbalanced salt solution enriched with bicarbonate, dextrose, and glutathione
NDAIRRIGATIONSOLUTION
Approved
Oct 1981
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
2
Data completeness
3/8 — Basic
BSS PLUS (balanced salt solution enriched with bicarbonate, dextrose, and glutathione) by Alcon is clinical pharmacology none of the components of bss plus are foreign to the eye. First approved in 1981.
Drug data last refreshed 9h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
BSS PLUS is an enriched balanced salt solution containing bicarbonate, dextrose, and glutathione for intraocular irrigation during ophthalmic surgery. It maintains corneal endothelial integrity and retinal electrical activity during procedures such as vitrectomy, phacoemulsification, and cataract extraction. The formulation uses physiologic ionic composition and pH to protect delicate ocular tissues during prolonged surgical manipulation.
LOE Approaching
As LOE approaches, commercial teams will shift focus from growth initiatives to defending market share against generic/biosimilar competition and managing portfolio transition.
Mechanism of Action
CLINICAL PHARMACOLOGY None of the components of BSS PLUS are foreign to the eye. Human perfused cornea studies have shown BSS PLUS to be an effective irrigation solution for providing corneal detumescence and maintaining corneal endothelial integrity during intraocular perfusion. An in vivo study…
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (2)
Safety of NGOIS Compared to BSS Plus in Pediatric Patients
Started Jul 2006
18 enrolled
Cataract
Safety and Efficacy of Next Generation Ophthalmic Irrigating Solution Compared to BSS Plus
Started Sep 2004
369 enrolled
Cataract
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.