NDAORALTABLET
Approved
Jun 2005
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Mechanism of Action
established. Isosorbide dinitrate is a vasodilator affecting both arteries and veins. Its dilator properties result from the release of nitric oxide and the subsequent activation of guanylyl cyclase, and ultimate relaxation of vascular smooth muscle. Several well-controlled clinical trials have…
Pharmacologic Class:
Nitrate Vasodilator