NDAINJECTIONINJECTABLE
Approved
Dec 1958
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
BICILLIN L-A (penicillin g benzathine) by Thayer Medical is mechanism of action penicillin g exerts a bactericidal action against penicillin-susceptible microorganisms during the stage of active multiplication. First approved in 1958.
Drug data last refreshed 10h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
BICILLIN L-A (Penicillin G Benzathine) is a long-acting injectable penicillin antibiotic approved in 1958 that treats bacterial infections caused by penicillin-susceptible organisms. It works by inhibiting bacterial cell-wall peptidoglycan synthesis, rendering the cell wall osmotically unstable and causing bactericidal activity. This classic antibiotic remains a cornerstone therapy for streptococcal infections including acute strep throat and rheumatic fever prophylaxis.
$4.0MPart D
LOE ApproachingStable
Low commercial activity with minimal Part D claims signals a mature, declining franchise requiring focused market defense strategies rather than growth initiatives.
Mechanism of Action
Mechanism of Action Penicillin G exerts a bactericidal action against penicillin-susceptible microorganisms during the stage of active multiplication. It acts through the inhibition of biosynthesis of cell-wall peptidoglycan, rendering the cell wall osmotically unstable.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Working on BICILLIN L-A offers limited career growth upside given zero linked job openings and approaching loss of exclusivity, but provides deep expertise in legacy antibiotic commercialization, formulary defense, and mature market management. This role suits professionals seeking to specialize in niche, high-compliance therapeutic areas or transition toward market access and payer strategy.
Brand Manager
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.