NDAINJECTIONINJECTABLE
Approved
Jun 1952
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
Drug Shortage Active
BICILLIN L-A is currently in shortage. Reason: Available. This may impact manufacturing, supply chain, and quality hiring at the manufacturer.
BICILLIN L-A (penicillin g benzathine) by Pfizer is mechanism of action penicillin g exerts a bactericidal action against penicillin-susceptible microorganisms during the stage of active multiplication. First approved in 1952.
Drug data last refreshed 13h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
BICILLIN L-A (Penicillin G Benzathine) is a long-acting injectable antibiotic approved in 1952 that treats bacterial infections caused by penicillin-susceptible organisms. It works by inhibiting bacterial cell-wall peptidoglycan biosynthesis, rendering the cell wall osmotically unstable and exerting bactericidal action during active microbial multiplication. This classic antibiotic remains a foundational treatment for streptococcal and other gram-positive infections.
LOE Approaching
As a mature product approaching loss of exclusivity with moderate competitive pressure (30), the brand team is likely focused on defending market share and managing generic transition rather than expansion.
Mechanism of Action
Mechanism of Action Penicillin G exerts a bactericidal action against penicillin-susceptible microorganisms during the stage of active multiplication. It acts through the inhibition of biosynthesis of cell-wall peptidoglycan, rendering the cell wall osmotically unstable.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Career opportunities on BICILLIN L-A are limited (0 linked jobs), reflecting the product's mature, stable status with no active growth initiatives. Roles available typically focus on supply chain management, regulatory compliance, and defending market position during the LOE transition.
Brand Manager
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.