NDAINJECTIONINJECTABLE
Approved
Jun 1952
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
3/8 — Basic
Drug Shortage Active
BICILLIN L-A is currently in shortage. Reason: Available. This may impact manufacturing, supply chain, and quality hiring at the manufacturer.
BICILLIN L-A (penicillin g benzathine) by Pfizer is mechanism of action penicillin g exerts a bactericidal action against penicillin-susceptible microorganisms during the stage of active multiplication. First approved in 1952.
Drug data last refreshed 5h ago · AI intelligence enriched 1mo ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
BICILLIN L-A (Penicillin G Benzathine) is a long-acting injectable penicillin antibiotic approved in 1952 that treats bacterial infections caused by penicillin-susceptible organisms. It works by inhibiting bacterial cell-wall peptidoglycan synthesis, rendering the cell wall osmotically unstable and killing susceptible bacteria. This product is a foundational antibiotic for conditions including streptococcal infections and syphilis.
LOE Approaching
As a legacy antibiotic approaching loss of exclusivity with moderate competitive pressure, teams are typically lean and focused on defending market share through supply chain reliability rather than innovation-driven growth.
Mechanism of Action
Mechanism of Action Penicillin G exerts a bactericidal action against penicillin-susceptible microorganisms during the stage of active multiplication. It acts through the inhibition of biosynthesis of cell-wall peptidoglycan, rendering the cell wall osmotically unstable.
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Career Relevance
Working on BICILLIN L-A offers exposure to legacy product stewardship, supply-chain criticality management, and defensive commercial strategy in a well-established market. Career progression is best suited to those interested in operational excellence, regulatory navigation, and maintaining market position rather than growth innovation or new product launches.
Supply Chain Manager
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.