NDAINJECTIONINJECTABLE
Approved
May 1953
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
5/8 — Partial
BICILLIN C-R (penicillin g benzathine and penicillin g procaine) by Pfizer is mechanism of action penicillin g exerts a bactericidal action against penicillin-susceptible microorganisms during the stage of active multiplication. Approved for the treatment of infections, the treatment of the following in pediatric patients: moderately severe to severe infections of the upper-respiratory tract, scarlet fever and 3 more indications. First approved in 1953.
Drug data last refreshed 9h ago · AI intelligence enriched Yesterday
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
BICILLIN C-R is a combination injectable penicillin product containing penicillin G benzathine and penicillin G procaine, approved in 1953. It treats moderately severe to severe infections of the upper respiratory tract, scarlet fever, erysipelas, and skin/soft-tissue infections caused by susceptible streptococci, primarily in pediatric patients. The drug works by inhibiting bacterial cell-wall peptidoglycan synthesis, rendering the cell wall osmotically unstable and causing bacterial death.
$0.035BPart D
LOE ApproachingLow-cost legacy product with minimal commercial spending and declining market relevance; expect small, stable brand team focused on maintenance.
Mechanism of Action
Mechanism of Action Penicillin G exerts a bactericidal action against penicillin-susceptible microorganisms during the stage of active multiplication. It acts through the inhibition of biosynthesis of cell-wall peptidoglycan, rendering the cell wall osmotically unstable resulting in death of the…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.