NDAORALSUSPENSION
Approved
Nov 1951
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
1
Data completeness
4/8 — Partial
BICILLIN (penicillin g benzathine) by Thayer Medical is mechanism of action penicillin g exerts a bactericidal action against penicillin-susceptible microorganisms during the stage of active multiplication. Approved for the treatment of infections due to penicillin-g-sensitive microorganisms, very prolonged serum levels common to this particular dosage form. First approved in 1951.
Drug data last refreshed 20h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
BICILLIN is penicillin G benzathine oral suspension approved in 1951 for treatment of penicillin-G-sensitive microbial infections. The drug exerts bactericidal action by inhibiting cell-wall peptidoglycan biosynthesis, rendering bacterial cell walls osmotically unstable. It is characterized by very prolonged serum levels unique to this benzathine formulation.
LOE Approaching
This legacy oral penicillin faces imminent loss of exclusivity with moderate competitive pressure (30), signaling a contracting team focused on defensive positioning and market maintenance rather than growth initiatives.
Mechanism of Action
Mechanism of Action Penicillin G exerts a bactericidal action against penicillin-susceptible microorganisms during the stage of active multiplication. It acts through the inhibition of biosynthesis of cell-wall peptidoglycan, rendering the cell wall osmotically unstable.
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.